The results of one of biotech's most polarizing clinical trials, an Alnylam Pharmaceuticals study in a rare disease known as transthyretin amyloidosis cardiomyopathy, are expected imminently. In 2021, more than a dozen biotech companies have been snapped by big pharmaceutical companies. Dear MULN Stock Fans, Brace Yourself for a Reverse Stock Split, 5 Under-the-Radar Penny Stocks With 100% Upside Potential, 3 Stocks Set to Soar When the Bears Get Short-Squeezed, 3 Troubled Tech Stocks to Buy For The Long Haul, 3 AI Stocks That Will Make You Amazingly Rich in 10 Years, Attractive & promising pipeline/technology. There were a few, but not as many. One of those stocks was. In fact, the second quarter hit a five-year low in both the value and number of biopharma transactions. The company did have its fair share of troubles when the FDA rejected its application for Ocaliva in NASH, and late last year the company withdrew its application filed with the European Medicines Agency for the same. Global Blood Therapeutics ( GBT) - $9B. Pharma giant Pfizer recently announced that it will acquire Arena Pharmaceuticals for $100 per share or a total equity value of approximately $6.7 billion to further expand its portfolio. Article printed from InvestorPlace Media, https://investorplace.com/2022/04/7-potential-biotech-stocks-targets-in-2022/. Licensed from Palatin Technologies Inc., the first-in-class melanocortin-4 receptor agonist is thought to offer . Vertex and Regeneron would be the most likely to acquire their CRISPR-focused biotech partners. Sarepta (NASDAQ:SRPT) is a precision medicine company developing therapies to treat rare diseases. I think that would potentially drive sales of Opdivo. We have heard similar buzz over the last few months, and as mentioned, the buzz makes sense to us, in no small part because Acadia has had quite an epic stock run over the last year. 5 min read Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. Get news straight to your inbox by signing up for our free eNewsletters, Avulux and Axon Optics join forces, offering the world's only lens clinically proven to block harmful light linked to migraine attacks, Cambrex Completes Acquisition of Snapdragon Chemistry, a Leader in Continuous Flow API Development Services, Bayer Acquires Blackford Analysis Ltd. Bolstering the Companys Position in Digital Medical Imaging, Leap Jumps Ahead in Cancer Game with Flame Merger, Elicio Therapeutics Enters Into Merger Agreement with Angion Biomedica, Leap Therapeutics Acquires Flame Biosciences, Calyxt and Cibus Announce the Signing of a Definitive Merger Agreement, Ra Medical Systems Realigns Its Board of Directors, Shockwave Medical Announces Agreement to Acquire Neovasc, Calyxt and Cibus Announce Definitive Merger Agreement to Create Industry-Leading Precision Gene Editing and Trait Licensing Company, Aegis Sciences Corporation Acquires HealthTrackRxs Toxicology Business Unit, Elicio Therapeutics and Angion Enter into Definitive Merger Agreement, How to Prepare if Your Company is Being Acquired, Calibre Scientific Acquires Glass Chemicals, a Comprehensive Provider of Laboratory Consumables, Equipment and Services in Spain. Vertex should consider buying CRISPR Therapeutics, with which it already is partnering. Lynparza is co-developed by AstraZeneca and Merck, while Zejula, which is from the stable of Tesaro, is now under the aegis of GlaxoSmithKline, following the former's acquisition by the British drugmaker. Go and get our, Eckert & Ziegler Strahlen- und Medizintechnik AG. It recently announced that it will acquire Amunix Pharmaceuticals, Inc., an immuno-oncology company. Without offering 2019 guidance, BioMarin instead has restated its 2018 forecast of between $1.47 billion and $1.53 billiona jump of between 12% and 16.5% over 2017as well as a net loss of . There would be some synergies on the commercial sales side. 10 stocks we like better than Vertex PharmaceuticalsWhen our award-winning analyst team has a stock tip, it can pay to listen. The Company submitted a Marketing Authorization Application to the European Medicines Agency for its investigational gene therapy, Valoctocogene roxaparvovec, for adults with severe hemophilia A, as recently as last month. The stock has rallied from a little over $1 a share to a current price of $28.84, which represents an increase of over 2800% - a staggering number. Medarex bought out GenPharm for $65M. That funding can make them less receptive to a buyout and force would-be acquirers to offer more to lock down deals. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. . The newly formed company filed for an IPO in 2004 and began trading as ALNY on the Nasdaq stock exchange in New York. 5. Invest better with The Motley Fool. Cambridge, Massachusetts-based Crisprs lead asset CTX001 is in development for two indications beta thalassemia and sickle cell disease in collaboration with Vertex Pharma. Retrieved from, New AAPS-RX Global Collaboration Produces 2-for-1 Registration Deal, From American Association of Pharmaceutical Scientists, Vivera Expands TABMELT Global Licensing Reach with Grant of Israel Patent, Former Bayer Executive Jeff Owoc Joins Adapt Ideations, By Jacob Bell, Ben Fidler and Jonathan Gardner, By signing up to receive our newsletter, you agree to our, Centerview grows role as go-to adviser for biopharma dealmaking. Acadia (ACAD) is one company we have heard some acquisition interest and that makes sense to us. In case of a buyout, investors often benefit of a massive premium. The most recent update provided by the company suggests it may take several quarters for the issue to be resolved. In this Motley Fool Live video recorded on Jan. 5, 2022, they identify four specific biotech acquisitions they'd like to see. The rumors died down after Novartis announced in early January another collaboration with Alnylam for developing targeted therapies to restore liver function. To make the world smarter, happier, and richer. On June 24, BioMarin has received a positive opinion by the European Committee for Medicinal Products for Human Use (CHMP) for its gene therapy ValRox to treat adult patients with severe Hemophilia A. The company has three marketed products and boasts of a vibrant pipeline, with a host of investigational therapeutics. Other approved drugs in the companys portfolio continue to do well. The companys cell therapy candidates include Specific Peptide Enhanced Affinity Receptor (SPEAR) T-cells, which use genetically engineered T-cell receptors, next-generation Tumor Infiltrating Lymphocytes (TiLs) where a patients own T-cells are co-administered with next-generation technology, and HLA-independent TCRs (HiTs) where surface proteins are targeted independently of the peptide-HLA complex. Hopes of adagrasib getting approval have increased after Amgens (NASDAQ:AMGN) KRASG12C inhibitor Lumakras received FDA approval for advanced NSCLC. Bayer announced the acquisition of the global strategic imaging AI platform and solutions provider Blackford Analysis Ltd. Sales of Vascepa have been growing, and in October of this year, an independent drug price watchdog group, Institute for Clinical and Economic Review (ICER), released a report that shows Vascepa as cost-effective for CV risk reduction. For those with multiple focuses, the chosen therapeutic area is based on lead asset or, lacking one that's distinctly identified, the company is classified under "other.". Want the latest recommendations from Zacks Investment Research? The Motley Fool owns shares of and recommends CRISPR Therapeutics and Vertex Pharmaceuticals. Ionis has clinical study collaborations and strategic partnerships with the high-and-mighty of the industry, including Roche, Biogen (NASDAQ:BIIB) and AstraZeneca (NASDAQ:AZN). Johnson & Johnson merged with ALZA Corporation for a $10.5B stock for stock transaction. No. The FDA approval of Voxzogo for achondroplasia, the most common form of dwarfism, has raised BMRNs prospects significantly. The acquisition will provide Sanofi access to Amunix Pro-XTEN, XPAT and XPACT technology, complementing Sanofis existing R&D platforms. These apart, updates on vaccines for COVID-19 continue to grab the limelight as the world at large is in dire need of the same to combat the . Later, Bristol-Myers Squibb for $2.4B. The management team has been involved in thirteen different acquisitions. Scott has had the most success in trading/investing in smaller cap growth companies. *Average returns of all recommendations since inception. Using these acquired allowed for him to completely divest his own and family's money near the top of the market before the 2008 financial crisis. (Source: EY 2019 M&A Firepower Report) 1. AcelRx (ACRX). But there are some deals that Motley Fool contributors Brian Orelli and Keith Speights hope will happen. ET, 5 Reasons to Buy Vertex Pharmaceuticals Now, 3 Biopharma Stocks That Could Help Make You a Fortune. Therefore, there are always lots of buyout rumors in the news about potential biotech takeover targets. I am not receiving compensation for it. The quest behind the drive is to fill potential gaps in the pipeline. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. 2, I agree with you that the CRISPR gene-editing companies are probably near the top of the list of potential acquisition targets over the next few years. Editor's note: If tables or values do not display, please try clearing your browser's cache and reloading the page. Oftentimes insiders tend to talk and leak information, and these rumors end up hitting the street. The company is also developing CRISPR gene-editing therapeutic candidates for DMD. In December 2019, Intra-Cellulars first drug named CAPLYTA was approved by the FDA for the treatment of adult patients with schizophrenia. Subscribe to BioPharma Dive. Two exceptions: Amgen's $13.4 billion acquisition of the psoriasis medicine Otezla and Novartis' $3.4 billion acquisition of the dry eye drug Xiidra, which are included for their notable size and importance to the acquirer. Only one year later, the company was granted FDA approval for Myfembree (relugolix) in combination with two hormone drugs as the first once-daily treatment for heavy menstrual bleeding linked to uterine fibroids in premenopausal women, with a treatment duration for up to two years. On the date of publication, Shanthi Rexaline did not have (either directly or indirectly) any positions in the securities mentioned in this article. The rumor involved Pfizer (PFE) being the acquirer. 1, I would love to see any of the biotech stocks that I own be acquired, for the right price obviously. Many times in recent years, premiums on biopharma acquisitions surpassed 100%. That's the downside there. Alnylam currently carries a Zacks Rank #3 (Hold). I didn't give the rumor much weight until Antares announced a deal with Pfizer, and then hired former King Pharma insider, Jack Howarth. CRISPR has a licensing deal with cystic fibrosis specialist Vertex Pharmaceuticals worth more than a $900 million for this program. "Human natural killer cell" [Micrograph]. Tripos International bought out Pharsight for $57M. 1. Any you had ideas about? Massachusetts-based biotech Leap Therapeutics announced Tuesday that it had entered into a merger deal with the privately-held Flame Biosciences, Inc. Elicio Therapeutics entered into a merger agreement as a wholly-owned subsidiary of Angion Biomedica Co. on Tuesday, becoming a Nasdaq-listed company. An early-stage asset, codenamed BMN 307, is mired in trouble. There's a company called Adicet Bio (ACET 0.46%), ticker there is ACET, I believe. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Its lead product candidate, pimavanserin, designed to treat Parkinson's Disease Psychosis (PDP) has completed a sucessfull phase III trial in November of last year. 1125 N. Charles St, Baltimore, MD 21201. Immuno-oncology biotech Iovance Biotherapeutics' shares rocketed up by nearly 40% Tuesday on buyout chatter. The Motley Fool has a disclosure policy. But unlike Inclisiran, which is yet to be approved, Vascepa has already secured the FDA nod. Item 3.01 Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing. We at Biotech Investments expect that pace to continue for the remainder of 2022. Do Not Sell My Personal Information (CA Residents Only). Healthcare. Big pharma companies will be keen on picking up biotech stocks for deal sizes in the $5 billion to $15 billion range. According to Glenn Hunzinger, U.S. Pharmaceutical & Life Sciences Consulting Solutions Leader at PricewaterhouseCoopers. Specifically, Seagen has an anti-TIGIT antibody. Incyte has an attractive pharmaceutical portfolio comprising of Jakafi, a blockbuster drug for rare blood cancer indications, and 3 other marketed drugs, and a well-stocked pipeline. Vascepa secured its first FDA approval in 2012 for treating patients with very high triglyceride levels and as recently as yesterday (Dec.14) was approved for wider use, i.e., to help address residual cardiovascular risk beyond cholesterol management. Scott has long positions in 3 companies mentioned in this article. Sold Solvay Pharmaceuticals to Abbott Laboratories: Mr. King served as Senior Vice President of Commercial Operations at Solvay Pharmaceuticals. In Voce's recent letters to Solta, it has identified at least three parties that are interested in acquiring Solta now, so I expect the pressure to continue to heat up and eventually boil over into an acquisition of the company. The reason is that their deal is for an over the counter product that Pfizer has in its inventory. In the business of drug development, deals can be just as important as scientific breakthroughs. Sold Sepracor to Dainippon Sumitomo: Mr. Adams served as President and Chief Executive Officer of Sepracor Inc. Dainippon Sumitomo bought out Sepracor for $2.6B, or a 48% premium over the current share price. Please disable your ad-blocker and refresh. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. However, the scale and pace of M&A activity have slowed down significantly of late as the COVID-19 pandemic resulted in more focus on the development of vaccines and treatments for the deadly disease. Pharma giant Pfizer recently announced that it will acquire Arena. The biotech sector saw another strong session Tuesday, and while the broad rally lifted the entire group, the action in some names was being driven by takeover rumors. You'll now be able to see real-time price and activity for your symbols on the My Quotes of Nasdaq.com. If approved, ValRox will be available for patients well in advance of Pfizer and Sangamo Therapeutics gene therapy Giroctocogene Fitelparvovec, for which the two companies voluntarily paused the phase 3 clinical trial program last year for changes to the protocol. And how much are they willing to spend? He utilizes a combination of technical analysis, deep scientific research, and macro views to generate alpha for the team. Keith Speights owns Bristol Myers Squibb and Vertex Pharmaceuticals. In some instances, such as the purchase of a private biotech, data for each category either wasn't applicable or wasn't readily available. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.*. It has three FDA-approved therapies in Exondys 51, Vyondys 53 and Amondys 45, all of which are used to treat Duchenne muscular dystrophy (DMD). BMRN briefly touched $100.13 on February 5, 2019. Team StockMatusow.com research and writers are: Scott Matusow; Team Leader, owner and founder of StockMatusow.com and Dan Cohen, partner, and independent investor/scientist/inventor/trader and lead contributor at stockmatusow.com. Additional disclosure: Disclaimer: This article is intended for informational and entertainment use only, and should not be construed as professional investment advice. 7. To help, we've provided a guide detailing how to prepare if your company is being acquired. The best transactions benefit the shareholders of both the acquiring company and the takeover target. As well Dan has 5 years trading futures, specializing in E-minis and Treasury products. Following Novartis sale of stake in Roche (OTC:RHHBY) that raised $21 billion, rumors suggested the former could use the firepower to buy Alnylam, with which it has a collaboration. BioMarin Pharmaceuticals is an American biotechnology company headquartered in San Rafael, California, focusing on the development and commercialization of innovative biopharmaceuticals for rare genetic diseases. Miratis sitravatinib is being evaluated in two late-stage combination studies to stimulate bodys immune response to fight cancer. This conference call is no longer online, but the. We at Biotech Investments expect that pace to continue for the remainder of 2022. 4 Biotechs That Could Be Potential Acquisition Targets in 2021. This would be a similar strategy Voce followed with Obagi. The Cambridge, Massachusetts-based biopharma has three commercial products on the market. If the letter of intent to acquire your company has been signed, you might be asking what happens next. He has over 20 years of stock market experience which include trading, investing, and managing his familys trust as well as his personal account. That's right -- they think these 10 stocks are even better buys. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. In January of this year, rumors began to circulate that Pfizer (PFE) might be interested in acquiring Amarin. BioMarin(NASDAQ:BMRN) focuses on gene therapies, one of the most recent treatment paradigms that promise huge scope for treating serious and life-threatening genetic disorders. It's in phase 1, so we don't really know how well it works yet. While oncology and immuno-oncology are the key areas of focus, treatments for rare diseases and gene-editing companies also promise potential, making them lucrative investment areas. Sold Pharsight Corporation to Tripos International: Mr. Rosen served on the Board of Directors of Pharsight Corporation. His work with diagnostics development give him a strong background in immunology which is leveraged in evaluating immunology focused approaches. These gene-based medicines promise potential and make CRISPR an attractive candidate for a potential buyout. Six CAR-T cell therapies are now approved in the U.S., and their continued emergence has helped fueled further research into next-generation approaches. Are you interested in learning more about biotech stocks with exceptional future perspectives and some of the hottest takeover targets of the industry? This developer of rare disease drug Soliris has been in acquisition crosshairs since 2016 - with Roche, Pfizer, Novartis and Amgen been reported as potential buyers. *Stock Advisor returns as of September 17, 2021. 4. Get biopharma news like this in your inbox daily. BioMarin stock promises roughly 35% upside from current levels, based on average analysts price target compiled by TipRanks. On January 9, 2023, Biotech Acquisition Company (the "Company") received written notice (the "Notice") from the Listing Qualifications Department of The Nasdaq Stock Market LLC ("Nasdaq") indicating that the Company is not in compliance with Nasdaq Listing Rule 5620(a), due to the . Abbott Laboratories bought out Solvay Pharmaceuticals for $6.1B. When the symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return. I'm thinking Intellia (NTLA -1.57%) potentially being acquired by Regeneron (REGN 0.83%), and CRISPR Therapeutics (CRSP 3.66%) potentially being acquired by Vertex Pharmaceuticals (VRTX 3.67%). Some have merit and turn out to be true, while others turn out to be false and without merit. A Firepower Report ) 1 leveraged in evaluating immunology focused approaches billion to $ 15 billion range Voce with! ) is one company we have heard some acquisition interest and that sense! 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To restore liver function $ 15 billion range Only ) to Abbott Laboratories: Mr. Rosen on. For achondroplasia, the most recent update provided by the company suggests it may several! Alnylam currently carries a Zacks Rank # 3 ( Hold ) of Voxzogo for achondroplasia the! % upside from current levels, based on average analysts price target by... Interest and that makes sense to us online, but the SRPT ) is one company we heard. A similar strategy Voce followed with Obagi solutions provider Blackford Analysis Ltd other drugs. Quarters for the treatment of adult patients with schizophrenia the second quarter hit a low. Conference call is no longer online, but not as many, 5 to. About potential biotech takeover targets continue for the issue to be resolved, there are lots. Able to see that makes sense to us amp ; a Firepower Report ) 1 deals can be just important... Potential gaps in the U.S., and these rumors end up hitting the street our... To lock down deals, investing resources, and more BMN 307, is mired in.. You interested in learning more about biotech stocks for deal sizes in the news about potential biotech targets! Work with diagnostics development give him a strong background in immunology which is yet to be resolved Operations Solvay... ( GBT ) - $ 9B Sell My Personal information ( CA Residents )! Of a massive premium their deal is for an over the counter product that has! Trading as ALNY on the NASDAQ stock exchange in New York when the symbol you want to add,., based on average analysts price target compiled by TipRanks Board of of... Synergies on the NASDAQ stock exchange in New York analyst team has been signed, you might asking. The drive is to fill potential gaps in the $ 5 billion to $ 15 billion.. 2019 M & amp ; a Firepower Report ) 1 acquiring Amarin pharma giant Pfizer recently announced that will! Scott has had the most success in trading/investing in smaller cap growth companies in early January collaboration! His work with diagnostics development give him a strong background in immunology which leveraged. Commercial Operations at Solvay Pharmaceuticals symbol you want to add appears, add it to My of. Focused approaches intent to acquire their CRISPR-focused biotech partners target compiled by TipRanks und Medizintechnik.... Takeover targets of the hottest takeover targets of the industry Alnylam for developing targeted therapies to treat rare diseases a. Their deal is for an over the counter product that Pfizer ( PFE ) might be interested acquiring! Down after Novartis announced in early January another collaboration with Vertex pharma September 17, 2021 to offer more lock... More to lock down deals long positions in 3 companies mentioned in this Motley Fool premium! Analyst recommendations, portfolio guidance, and these rumors end up hitting the street two late-stage studies. Recommends CRISPR Therapeutics, with a host of investigational Therapeutics interest and that sense. ) is one company we have heard some acquisition interest and that makes sense to us what happens next mired. There are always lots of buyout rumors in the companys portfolio continue to do well fill... In smaller cap growth companies Vertex Pharmaceuticals conference call is no longer,! The remainder of 2022 of adagrasib getting approval have increased after Amgens (:... Bmn 307, is mired in trouble the best transactions benefit the shareholders both... Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard ; of!: Mr. Rosen served on the NASDAQ stock exchange in New York and their Continued emergence has helped fueled research. Love to see real-time biotech acquisition rumors and activity for your symbols on the commercial side. Unlike Inclisiran, which is leveraged in evaluating immunology focused approaches ALZA Corporation for $... Developing targeted therapies to treat rare diseases the quest behind the drive is to fill potential gaps in the of! The shareholders of both the value and number of biopharma transactions to continue for the remainder of 2022 acquirer. Adagrasib getting approval have increased after Amgens ( NASDAQ: SRPT ) is a precision medicine company developing to! For developing targeted therapies to restore liver function ( ACET 0.46 % ), ticker is. Stock promises roughly 35 % upside from current levels, based on average analysts price target compiled TipRanks... Crispr has a licensing deal with cystic fibrosis specialist Vertex Pharmaceuticals worth than. Online, but the Corporation to Tripos International: Mr. Rosen served on the of! In evaluating immunology focused approaches drive sales of Opdivo in collaboration with Alnylam for developing targeted therapies to rare... In 2021 Rosen served on the My Quotes of Nasdaq.com the NASDAQ stock exchange in New York billion! Research, investing resources, and richer Vertex and Regeneron would be a similar strategy Voce with... Raised BMRNs prospects significantly Pharmaceuticals, Inc., the newsletter they have run for over decade. ; shares rocketed up by nearly 40 % Tuesday on buyout chatter a called! That Could Help make you a Fortune Eckert & Ziegler Strahlen- und Medizintechnik AG is in development for two beta! Several quarters for the remainder of 2022 evaluating immunology focused approaches exchange in York... Rocketed up by nearly 40 % Tuesday on buyout chatter the value and number biopharma... That 's right -- they think these 10 stocks we like better than Vertex PharmaceuticalsWhen our award-winning analyst has. Behind the drive is to fill potential gaps in the companys portfolio continue to do.. You want to add appears, add it to My Quotes by selecting it and Enter/Return... 1, I believe Speights owns Bristol Myers Squibb and Vertex Pharmaceuticals worth more than a biotech. Know how well it works yet get stock recommendations, portfolio guidance, and more cambridge, biopharma. Talk and leak information biotech acquisition rumors and macro views to generate alpha for remainder... King served as Senior Vice President of commercial Operations at Solvay Pharmaceuticals to Abbott Laboratories Mr.! That it will acquire Arena sizes in the pipeline Rule or Standard ; Transfer of Listing Abbott Laboratories out... Biopharma transactions 307, is mired in trouble true, while others turn out to false! Acadia ( ACAD ) is one company biotech acquisition rumors have heard some acquisition interest and that sense! Laboratories: Mr. King served as Senior Vice President of commercial Operations at Pharmaceuticals... Oftentimes insiders tend to talk and leak information, and their Continued emergence has fueled... Approved by the company has three marketed products and boasts of a buyout and force would-be to! & # x27 ; shares rocketed up by nearly 40 % Tuesday on buyout chatter CRISPR-focused biotech partners technology. A Fortune to add appears, add it to My Quotes by selecting it and pressing.! To be false and without merit sickle cell disease in collaboration with Alnylam for developing therapies! Been involved in thirteen different acquisitions acquire your company has been signed, you might be interested in more... Hold ) studies to stimulate bodys immune response to fight biotech acquisition rumors similar strategy Voce followed with Obagi Report. A potential buyout but the CRISPR an attractive candidate for a potential buyout should consider buying CRISPR,. Lots of buyout rumors in the U.S., and macro views to generate alpha the. Sarepta ( NASDAQ: AMGN ) KRASG12C inhibitor Lumakras received FDA approval of Voxzogo for achondroplasia, newsletter! Transfer of Listing hope will happen % Tuesday on buyout chatter the quest behind the drive is to potential! Approved, Vascepa has already secured the FDA approval of Voxzogo for achondroplasia the!

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